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  • CAR-T Trial Targets Glioblastoma Brain Cancer
    by Neuroscience News on 19 Aprile 2024

    Researchers initiated a pioneering clinical trial using an advanced form of CAR-T therapy, enhanced by synthetic notch (synNotch) technology, to treat glioblastoma. This trial represents a significant shift towards targeted, safer cancer therapies.

  • Eye Tests Predict Parkinson’s Progression
    by Neuroscience News on 19 Aprile 2024

    Optical coherence tomography, commonly used in eye exams, can monitor neurodegeneration in Parkinson's disease patients by measuring the thickness of the retina. This method has revealed that retinal degeneration often precedes cognitive and motor decline, offering a potential early indicator of disease progression.

  • Novel DNA Mechanism in Memory Discovered
    by Neuroscience News on 19 Aprile 2024

    Researchers identified a novel mechanism that impacts memory formation through changes in DNA structure, specifically G-quadruplex DNA (G4-DNA). Their study reveals that G4-DNA accumulates in neurons, dynamically influencing gene activation and repression crucial for long-term memory.

  • Blood Test Predicts Multiple Sclerosis Years Before Symptoms Appear
    by Neuroscience News on 19 Aprile 2024

    Researchers identified a specific pattern of autoantibodies in the blood that precedes the clinical onset of multiple sclerosis (MS), potentially paving the way for early diagnosis and treatment. Their study found that 10% of MS patients displayed a unique set of autoantibodies against both human proteins and common pathogens like the Epstein-Barr Virus years before showing symptoms.

  • CBD’s Neuroprotective Properties Explored
    by Neuroscience News on 18 Aprile 2024

    Summary: Cannabinol (CBN), a cannabinoid derived from cannabis, offers neuroprotective properties that could treat neurological disorders like Alzheimer’s, Parkinson’s, and traumatic brain injuries. Their study details how CBN and its newly developed analogs prevent mitochondrial dysfunction in neurons, a common factor in these diseases. The team synthesized four CBN-based compounds, finding one, in particular, to be highly effective in a fruit fly model of brain injury. These findings not only highlight CBN’s therapeutic potential but also pave the way for

  • Treatment Relieves Chronic Lyme Disease’s Neurological Symptoms
    by Neuroscience News on 18 Aprile 2024

    Fibroblast growth factor receptor inhibitors, commonly used in cancer treatment, could effectively reduce neurological symptoms in patients with post-treatment Lyme disease syndrome. The study shows these inhibitors can decrease inflammation and cell death in brain and nerve tissues affected by Lyme disease.

  • How Drugs Hijack the Brain’s Reward System
    by Neuroscience News on 18 Aprile 2024

    Researchers made significant advances in understanding how drugs like cocaine and morphine disrupt the brain's natural reward mechanisms. Their study reveals that these drugs manipulate the same brain cells responsible for processing natural rewards, leading to compulsive drug-seeking behaviors.

  • Training Enhances Word Recognition for Efficient Reading
    by Neuroscience News on 18 Aprile 2024

    Researchers developed a training method that enhances the recognition of known versus unknown words, thereby improving reading efficiency. Their study employs a model based on brain behavior that functions like a filter, distinguishing known words from unfamiliar letter combinations.

  • PTSD’s Genetic Roots: 43 Genes and 95 Loci Identified
    by Neuroscience News on 18 Aprile 2024

    A monumental genetic study involving over 1.2 million people has identified 95 genomic loci associated with PTSD, revealing 80 previously undiscovered loci. This study, the largest of its kind, highlights the significant genetic underpinnings of PTSD and suggests new avenues for treatment and prevention strategies.

  • Environment Shapes Emotional Cognitive Abilities More Than Genes
    by Neuroscience News on 18 Aprile 2024

    Environmental factors may have a more significant impact on certain cognitive abilities than genetics. The study involved 57 pairs of identical and 48 pairs of fraternal twins from the Beijing Twin Study, focusing on metacognition and mentalizing—abilities tied to understanding and controlling one's cognitive processes and recognizing emotions in others, respectively.

  • Autism’s Brain Structure Secrets Revealed
    by Neuroscience News on 17 Aprile 2024

    Researchers developed a groundbreaking approach using Diffusion MRI to explore the brain structures of individuals with autism spectrum disorder (ASD). This technique measures how water molecules move through the brain, revealing structural differences in the neural pathways of autistic versus non-autistic individuals.

  • Teen Emotions Deciphered by AI and Head-cam
    by Neuroscience News on 17 Aprile 2024

    Researchers developed a method using wearable headcams and AI to analyze teenagers' facial expressions, revealing subtle emotional nuances. This technology has shown potential in identifying emotions such as worry and happiness, even when they are masked.